Choose machines magic or family. The decision is easy as long as you have the intelligence.
For those who dabble in the magical arts and alchemy and/or decide to be more medieval we have these following mods to offer:
Thaumcraft
Witchery
Project E
Tinker's Construct
Mantle
For those of you who are hardcore adventurers here are the mods you may use:
Adventurer's Backpack
Spice of Life
Extra Utilities
Vanilla Plus
SG Craft
If you decide that you want to be a machine god here are the mods that will help you on your journey:
Thermal Foundation
Thermal Expansion
Computercraft
Big Reactors
Project Red
Modular Powersuits
Modular Powersuits Addons
Numina
Modular Forcefield Systems
Security Mod
Resonant Engine
RadixCore
Optifine
Applied Energistics
Galacticraft
Galacticraft Planets
Micdoodle Core
Mekanism
Build Craft
CoFH Core
Power Crystals Core
ICBM
Electrical Age
Voltz Engine
Mine Factory Reloaded
Nuclear Craft
RF Windmill
If you decide to not become a king of machines, monarch of magic, or an expert explorer. then these mods might be more in your range:
Musicraft
Carpenters Blocks
Flans Mod
Bilbo Craft
Dr.Zhark's Mo Creatures
GrothCraft
Minecraft Comes Alive
Mr Cray Fish's Furniture Mod
IvToolkit
Psychedelicraft
Other mods that have no catagory:
Item Physics
Tree Capitator
Shaders Mod
Immibis Mod
Zyins Hud
Those who wish to join forces of machines and magic here are the mods you may use:
Botania
Techonmacy